The game, which kicks off at 1:05 pm ET, will be played at Bills Stadium in Orchard Park, NY. The weather will be partly cloudy with a 2% chance of precipitation and winds at 6 mph from the WNW. The temperature at game time will be 33 degrees. Also, see our over/under for this Indy versus Buffalo contest.
Indianapolis vs Buffalo Pick – Offenses
Colts vs Bills Spread Pick – Defenses
Indianapolis vs Buffalo pick notes that the Colts are down a few defensive players, including potentially DT DeForest Buckner (9.5 SCKs, 13.5 TFL, 3 PD). He’s listed as being questionable. Plus, they will be without safety Khari Willis and corner Rock Ya-Sin. The Colt defense has scored five TDs while forcing 14 fumbles and recovering 10 and grabbing 15 picks. They’ve also made 40 sacks, 87.5 TFL, and 77 PD. Notably, defensive ends Justin Houston and Denico Autry have accumulated 8.0 and 7.5 sacks. Also, LB Darius Leonard tops the team with 86 solo tackles and 132 total bringdowns. He also has 3.0 sacks, 9.5 TFL, 7.0 PD, and 3.0 forced fumbles with 2.0 recovered. Corners Kenny Moore II (4 INTs, 12 PD, 1 TD) and Xavier Rhodes (2 INTs, 12 PD, 1 TD) lead what is a solid secondary. Consequently, the Colts are allowing on average 22.6 PPG.
On the other hand, the Bills are allowing on average 23.4 PPG. Of note, Buffalo has recorded 38 sacks, 97 TFL, and 15 INTs. Along with 76 PD, this defense has forced 15 rumbles, recovering 11 and scored three TDs. In the secondary, corner Tre’Davious White has three picks, 11 PD, and one forced and two recovered fumbles. DE Jerry Hughes (4.5 SCKs, 7.5 TFL), LB Matt Milano (3.5 SCKs, 4.5 TFL), and DE Mario Addison (5.0 SCKs, 7.5 TFL) are premium defenders. Consequently, each will need to play well today. Plus, safety Jordan Poyer tops the team with 91 solo tackles and 124 total tackles. Additionally, Poyer has made 2.0 sacks, 6.5 TFL, 2 INTs, and 5 PD.
Indianapolis vs Buffalo Pick – Final Word
Our Indianapolis vs Buffalo pick does like Buffalo’s Josh Allen-run offense. Allen has become a premium performer. He’s a true playmaker. Of course, Buffalo’s Diggs and Beasley are exceptionally important factors as far as this offense is concerned. Colt QB Rivers can bring it. He has a fine receiving unit. However, we prefer the Bill offense in this contest. On the other side of the ball, we find that the Buffalo D is deep. Please see our other wildcard picks for today, including Los Angeles vs Seattle and Tampa Bay vs Washington.
Indianapolis Colts vs Buffalo Bills Summary
Buffalo Bills at -6.0 (-120)